Hereditary colorectal cancer.

By H. Lynch, A. de la Chapelle. New England Journal of Medicine, 2003

828 citations recorded by the source corpus.

Subfields: Cancer Research, Oncology, Pathology and Forensic Medicine

View Paper: https://www.semanticscholar.org/paper/13f9e51529c94a67a9f1cd37350c7f013aa5759a

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cancer Research

1. Bert Vogelstein
2. C. Tomasetti
3. Benjamin L. Ebert
4. Siddhartha Jaiswal

In Oncology

1. Bert Vogelstein

In Pathology and Forensic Medicine

1. Bert Vogelstein
2. Benjamin L. Ebert
3. Siddhartha Jaiswal

Citations in the corpus

• Variation in cancer risk among tissues can be explained by the number of stem cell divisions (2015, background): “Colorectal adenocarcinoma in patients with HNPCC HNPCC (Hereditary Non-polyposis Colorectal Cancer, also called Lynch Syndrome) accounts for 1-3% of colorectal cancers, and the lifetime risk of colorectal cancer for those with HNPCC has been estimated to be ~50% (61), (62).”
• Heritable somatic methylation and inactivation of MSH2 in families with Lynch syndrome due to deletion of the 3′ exons of TACSTD1 (2009, background): “283" language="eng" relation="no"> Lynch syndrome patients are susceptible to colorectal and endometrial cancers owing to inactivating germline mutations in mismatch repair genes, including MSH2 (ref”