Conducting Polymers for Tissue Engineering

By Baolin Guo, P. Ma. Biomacromolecules, 2018

684 citations recorded by the source corpus.

Electrically conducting polymers such as polyaniline, polypyrrole, polythiophene and their derivatives (mainly aniline oligomer and poly(3,4-ethylenedioxythiophene)) with good biocompatibility find wide applications in biomedical fields including bioactuators, biosensors, neural implants, drug delivery systems and tissue engineering scaffolds. This review focuses on these conductive polymers for tissue engineering application. Conductive polymers exhibited promising conductivity as bioactive scaffolds for tissue regeneration and their conductive nature allows cells or tissue cultured on them to be stimulated by electrical signals. However, their mechanical brittleness and poor processability restrict their application. Therefore, conductive polymeric composites based on conductive polymers and biocompatible biodegradable polymers (natural or synthetic) were developed. The major objective of this review is to summarize the conductive biomaterials used in tissue engineering including conductive composite films, conductive nanofibers, conductive hydrogels, and conductive composite scaffolds fabricated by various methods such as electrospinning, coating or deposition by in situ polymerization. Furthermore, recent progress in tissue engineering applications by using these conductive biomaterials including bone tissue engineering, muscle tissue engineering, nerve tissue engineering, cardiac tissue engineering, and wound healing application are discussed in detail.

Subfields: Biomaterials, Biomedical Engineering, Polymers and Plastics

View Paper: https://www.semanticscholar.org/paper/134057dd9ca16f3900a015603d75a5b45b596026

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In Biomaterials

  1. Rui Yu
  2. Hualei Zhang
  3. Baolin Guo

In Biomedical Engineering

  1. Baolin Guo

In Polymers and Plastics

  1. Baolin Guo

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