Opioid epidemic in the United States.

By L. Manchikanti, S. Helm, B. Fellows, J. Janata, V. Pampati, J. Grider, M. Boswell. Pain Physician, 2012

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Wide Variation and Excessive Dosage of Opioid Prescriptions for Common General Surgical Procedures (2017, background): “It has been noted that although most of these pills originated from a licensed prescriber, only 20% of users were the legitimate recipient of the initial prescription, with 71% of users having received the drug through methods of diversion.(4,10) In addition, it is reported that 55% of these people ”
Trends in Prescription Drug Use among Adults in the United States from 1999–2012 (2015, unknown): “5-13] 25-<30 1684 939 (57) [52-62] 245 (12) [10-15] 30-<35 1066 1066 (62) [58-66] 212 (17) [15-19] 35-<40 451 284 (68) [60-75] 109 (24) [18-30] ≥40 354 250 (73) [66-78] 117 (29) [24-35] a All paticipants were aged 20 years or older.”
A Meta-Analysis of the Relationship Between Sleep Problems and Loneliness (2020, background): “For example, social-media usage ( Jackson & Wang, 2013), individualism and family fragmentation (Lykes & Kemmelmeier, 2014), opioid use problems (Manchikanti et al., 2012), increasing suicide rates (Curtin, Warner, & Hedegaard, 2016), and vigilance associated with gun ownership (Karp, 2018) may all ”