Endothelin system: the double-edged sword in health and disease.

By R. Kedzierski, M. Yanagisawa. Annual Review of Pharmacology and Toxicology, 2001

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Molecular distinction between physiological and pathological cardiac hypertrophy: experimental findings and therapeutic strategies. (2010, background): “ETA receptors account for 90% of endothelin receptors on cardiac myocytes (Kedzierski & Yanagisawa, 2001).”
Endothelial cell functions (2003, background): “…complementary endothelial ligand for Mac-1 is intercellular adhesion molecule-1 (ICAM-1), an Ig-like molecule that exhibits low constitutive presentation of endothelial cell membranes, but is markedly induced by exposure of endothelial cells to cytokines (Klein et al., 1995; Scholz et al., 1996).”
Endothelial Dysfunction and Hypertension. (2016, background): “Both of these receptors are coupled to a G-pro tein and to the formation of IP3 (Barton 2011; Kedzierski and Yanagisawa 2001).”