Ventilation–Perfusion Scintigraphy Is More Sensitive than Multidetector CTPA in Detecting Chronic Thromboembolic Pulmonary Disease as a Treatable Cause of Pulmonary Hypertension

By N. Tunariu, S. Gibbs, Z. Win, W. Gin-Sing, A. Graham, P. Gishen, A. Al-Nahhas. Journal of Nuclear Medicine, 2007

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Pulmonary arterial hypertension (2013, methodology): “Indeed, V/Q lung scan is the method of choice to detect CTEPH [188] and normal V/Q scan can eliminate CTEPH.”
ESC Guidelines on the diagnosis and management of acute pulmonary embolism (2014, methodology): “While MDCT angiography is the investigation of choice for the diagnosis of acute PE, planar V/Q lung scan remains the main first-line imaging modality for CTEPH, as it carries a 96–97% sensitivity and 90–95% specificity for the diagnosis.(395) By contrast, in iPAH and pulmonary veno-occlusive diseas”
[2014 ESC Guidelines on the diagnosis and management of acute pulmonary embolism]. (2014, positive): “While MDCT angiography is the investigation of choice for the diagnosis of acute PE, planar V/Q lung scan remains the main first-line imaging modality for CTEPH, as it carries a 96–97% sensitivity and 90–95% specificity for the diagnosis.(395) By contrast, in iPAH and pulmonary veno-occlusive diseas”
2019 ESC Guidelines for the diagnosis and management of acute pulmonary embolism developed in collaboration with the European Respiratory Society (ERS) (2019, background): “Planar V/Q lung scan is a suitable first-line imaging modality for CTEPH as it has 96 97% sensitivity and 90 95% specificity for the diagnosis.(455) SPECT seems less sensitive than planar V/Q scanning if assessed at a level of individual segmental arteries, but it is unlikely to miss clinically rele”