Direct electrochemistry and electrocatalysis of hemoglobin based on poly(diallyldimethylammonium chloride) functionalized graphene sheets/room temperature ionic liquid composite film

By Kunping Liu, Jingjing Zhang, Guohai Yang, Chunming Wang, Jun‐Jie Zhu. 2010

284 citations recorded by the source corpus.

Abstract The functionalized graphene nanosheets (PDDA-G) with poly(diallyldimethylammonium chloride) (PDDA) were synthesized and used to combine with room temperature ionic liquid (RTIL). The resulting RTIL/PDDA-G composite displayed an enhanced capability for the immobilization of hemoglobin to realize its direct electrochemistry. Moreover, the RTIL/PDDA-G based biosensor exhibited excellent electrocatalytic activity for the detection of nitrate with a wide linear range from 0.2 to 32.6 μM and a low detection limit of 0.04 μM at 3σ. This work opens a new way to functionalized graphene nanosheets with good biocompatibility and solubility in biosensors.

Subfields: Electrical and Electronic Engineering, Materials Chemistry, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/120a0f5d6465968dd1af18043679b2451afd31b1