The anaplastic lymphoma kinase in the pathogenesis of cancer

By R. Chiarle, C. Voena, C. Ambrogio, R. Piva, G. Inghirami. Nature Reviews. Cancer, 2008

888 citations recorded by the source corpus.

Subfields: Genetics, Oncology, Pathology and Forensic Medicine

View Paper: https://www.semanticscholar.org/paper/1144da5c99205d29b704ca1c227799552b70b472

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In Genetics

1. R. Weinberg

In Oncology

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Citations in the corpus

• Oncogenic kinase NPM/ALK induces through STAT3 expression of immunosuppressive protein CD274 (PD-L1, B7-H1) (2008, background): “(1996) Characterization of the transforming activity of p80, a hyperphosphorylated protein in a Ki-1 lymphoma cell line with chromosomal translocation t (2; 5).”
• Clinical features and outcome of patients with non-small-cell lung cancer who harbor EML4-ALK. (2009, background): “microtubule-associated protein-like 4 (EML4) is fused to the intracellular kinase domain of anaplastic lymphoma kinase (ALK).(9) EML4-ALK possesses potent oncogenic activity both in vitro and in vivo.”