A PINOID-Dependent Binary Switch in Apical-Basal PIN Polar Targeting Directs Auxin Efflux

By Jir□í Friml, Xiong Yang, M. Michniewicz, Dolf Weijers, Ab Quint, O. Tietz, René Benjamins, P. Ouwerkerk, K. Ljung, G. Sandberg and 3 more. Science, 2004

821 citations recorded by the source corpus.

Subfields: Molecular Biology, Plant Science

View Paper: https://www.semanticscholar.org/paper/1110d6cd17cf63e82f84693d133c699e16dc6911

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Citations in the corpus

Auxin: regulation, action, and interaction. (2005, background): “PIN localization responds to cues from the PINOID serine-threonine kinase; PINOID overexpression or disruption alters the polar localization of PIN proteins in the cell (Friml et al., 2004).”
Patterns of Auxin Transport and Gene Expression during Primordium Development Revealed by Live Imaging of the Arabidopsis Inflorescence Meristem (2005, neutral): “Such an event may be mediated by the PINOID protein kinase [38, 39], since it is expressed in boundary domains and can act as a PIN1 polarity switch [30, 40 ].”
Antagonistic regulation of PIN phosphorylation by PP2A and PINOID directs auxin flux. (2007, background): “Genetic and pharmacological studies have indicated involvement of (de)phosphorylation processes in regulation of PIN-dependent auxin transport (Garbers et al., 1996; Benjamins et al., 2001; Friml et al., 2004; Shin et al., 2005).”
Flavonoids as Important Molecules of Plant Interactions with the Environment (2014, background): “PID plays the role of a switch influencing the PIN protein distribution in the cell membrane [158,159].”
Auxin transport routes in plant development (2009, background): “The current model is that PID phosphorylates PIN proteins, thus supporting their apical targeting, and that PP2A antagonizes this action, thus promoting basal PIN delivery (Friml et al., 2004; Michniewicz et al., 2007).”
Role of cytokinin and auxin in shaping root architecture: regulating vascular differentiation, lateral root initiation, root apical dominance and root gravitropism. (2006, background): “Polar accumulation of PIN proteins at specific sites of the plasma membrane enables detection of the polar IAA transport direction (Friml et al., 2002, 2004; Benková et al., 2003; Blilou et al., 2005).”
Functional redundancy of PIN proteins is accompanied by auxin-dependent cross-regulation of PIN expression (2005, background): “…pin1,2, pin1,7, PIN7::PIN7:GFP (Blilou et al., 2005), PIN7:GUS (Friml et al., 2003b), PIN2::PIN2:GFP (Xu et al., 2005), HS::axr3-1 (Knox at al., 2003), pin1 (Okada et al., 1991), slr-1 (Fukaki et al., 2002), agr1 (Chen et al., 1998) and eir1-1 (Luschnig et al., 1998) have been described previously.”
PIN-Dependent Auxin Transport: Action, Regulation, and Evolution (2015, background): “Conversely, the pid mutant exhibits the opposite, apical-to-basal, polarity switch of PIN1 in the shoot apical meristem (Friml et al., 2004), confirming the function of PID in PIN apical versus basal polarity determination.”
Intracellular trafficking and proteolysis of the Arabidopsis auxin-efflux facilitator PIN2 are involved in root gravitropism (2006, background): “Ectopic expression of the PINOID serine–threonine kinase causes similar effects that have been linked to deficiencies in the establishment of auxin gradient”
Model for the regulation of Arabidopsis thaliana leaf margin development (2011, background): “PID family proteins, previously shown to affect PIN1 localization (13), may play a role in these processes.”
Auxin: the looping star in plant development. (2008, background): “subcellular targeting of the constituent proteins is regulated by components involved in endosomal trafficking, and also depends on the phosphorylation status of the proteins, as well as on components that determine membrane composition (38, 44, 71, 135).”
A Role for Auxin in Flower Development (2007, background): “Other members of the ARF family in Arabidopsis including ARF1, ARF2, ARF6, and ARF8 recently have also been implicated in some aspects of flower development ( Ellis et al. 2005; Nagpal et al. 2005; Goetz et al. 2006; Schruff et al. 2006).”