Natural history of multiple sclerosis: a unifying concept.

By Christian Confavreux, Sandra Vukusic. Brain : a journal of neurology, 2006

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The neurobiology of multiple sclerosis: genes, inflammation, and neurodegeneration. (2006, background): “In a recently published natural history study, females reached disability endpoints at an older age than males (Confavreux and Vukusic, 2006a).”
Treatment of Multiple Sclerosis: A Review. (2020, neutral): “2020;383(6):546–557 [PubMed: 32757523] 28.”
Contrasting disease patterns in seropositive and seronegative neuromyelitis optica: A multicentre study of 175 patients (2012, background): “8 years) than that noted even in untreated exacerbatingremitting MS patients (23 years) [43].”
Meningeal inflammation is widespread and linked to cortical pathology in multiple sclerosis. (2011, methodology): “Previous work has demonstrated that an older age at disease onset (Vukusic and Confavreax, 2003), male gender (Confavreux and Vukusic, 2006a) and increased numbers of relapses in the first 2 years of disease (Scalfari et al., 2010) are associated with a shortened period between onset of symptoms…”