The role of falling leptin levels in the neuroendocrine and metabolic adaptation to short-term starvation in healthy men.

By J. Chan, K. Heist, A. DePaoli, J. Veldhuis, C. Mantzoros. Journal of Clinical Investigation, 2003

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The role of leptin and ghrelin in the regulation of food intake and body weight in humans: a review (2007, background): “Several studies have demonstrated that leptin is involved in the neuroendocrine response to starvation, including changes in hormone concentrations, and possibly changes in sympathetic nervous system activity and reproductive function (79,80).”
Narrative Review: The Role of Leptin in Human Physiology: Emerging Clinical Applications (2010, background): “Unlike in normal mice (24), leptin administration does not reverse the elevated adrenocorticotropin levels associated with starvation in humans (7).”
Physiology of leptin: energy homeostasis, neuroendocrine function and metabolism. (2015, background): “In addition, leptin levels fluctuate according to changes in calorie intake with a marked decrease during starvation [6, 7].”
Small differences in thyroid function may be important for body mass index and the occurrence of obesity in the population. (2005, background): “increase in thyroid secretion and in serum free T4 (24, 25).”
Deiodinases: implications of the local control of thyroid hormone action. (2006, neutral): “While dopamine and glucocorticoids play a suppressive role with respect to TSH (58), leptin administration leads to increases in serum TSH, T4, and T3 concentrations in fasting rats (59) and humans (60).”