Intention to participate in a COVID-19 vaccine clinical trial and to get vaccinated against COVID-19 in France during the pandemic

By M. Detoc, Sébastien Bruel, P. Frappé, B. Tardy, E. Botelho-Nevers, A. Gagneux-Brunon. medRxiv, 2020

598 citations recorded by the source corpus.

Background: The world is facing the COVID-19 pandemic. Development of vaccine is challenging. Aim: To determine the proportion of people who intend to get vaccinated against COVID-19 in France or to participate in a vaccine clinical trial. Methods: We conducted an anonymous on-line survey from the 26th of March to the 20th of April 2020. Primary endpoints were the intention to get vaccinated against COVID-19 if a vaccine was available or participate in a vaccine clinical trial. Results: Three thousand two hundred and fifty nine individuals answered the survey; women accounted for 67.4 % of the responders, 670 (20.6 %) were under 30 years of age, 1,502 (46.1 %) between 30-49 years, 803 (24.6 %) between 50-64 years, 271 (8.3%) between 65-80 years, 13 (0.4%) over 80 years of age. According to their statements, 2.512 participants (77.6%, 95 % CI 76.2-79 %) will certainly or probably agree to get vaccinated against COVID-19. Older age, male gender, fear about COVID-19, being healthcare workers and individual perceived risk were associated with COVID-19 vaccine acceptance Vaccine hesitancy was associated with a decrease in COVID-19 vaccine acceptance. One thousand and five hundred and fifty responders (47.6 % 95 % CI 45.9-49.3 %) will certainly or probably agree to participate in a COVID-19 vaccine clinical trial. Conclusions and Relevance: Nearly 75 % and 48 % of the survey responders were likely to accept vaccination or participation in a clinical trial against COVID-19. Vaccine hesitancy will be the major barrier to COVID-19 vaccine uptake.

Subfields: Health, Infectious Diseases, Obstetrics and Gynecology

View Paper: https://www.semanticscholar.org/paper/105b393cecbb526e6f7dbe314ff0a886316ef702

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Citations in the corpus

• Vaccine hesitancy in the era of COVID-19 (2021, unknown): “…vaccine were more likely to receive COVID-19 vaccine - Therewas a positive relationship between health engagement and willingness to vaccinate Detoc, 2020 France 26 March 2020e20 April 2020 Survey n/r 3259 COVID-19 - <30 years old 20.6% - 30e49 years old 46.11% - 50e64 years old 24.6% -…”
• Confidence and Receptivity for COVID-19 Vaccines: A Rapid Systematic Review (2020, background): “[18] [France] 2512 † If a vaccine against the new coronavirus was available for next season, would you get vaccinated? Yes, certainly/ yes, possibly/I don’t know/No, possibly/ Definitely no 24% 53.”