Studying protein dynamics in living cells

By Jennifer Lippincott-Schwartz, E. Snapp, A. Kenworthy. Nature reviews. Molecular cell biology, 2001

1,241 citations recorded by the source corpus.

Subfields: Biophysics, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/10429de546a84706285c0eed24f9ade5fc7ade51

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Citations in the corpus

Electron microscopy of specimens in liquid. (2011, background): “However, these processes can be imaged with light microscopy, for example through phase contrast microscopy of the native cellular material or fluorescence microscopy of labelled proteins or other components in cell”
Dynamics of proteins in solution (2019, methodology): “Using two dyes on two molecules, intermolecular docking can be studied in time (Lippincott-Schwartz et al., 2001; Piston and Kremers, 2007; Roy et al., 2008) as well as protein localizations in the cell (Sekar and Periasamy, 2003).”
Fluorescence lifetime imaging microscopy in life sciences (2010, methodology): “First, selective bleaching of the acceptor is required, because bleaching of the donor will result in underestimation of donor de-quenching [4, 104].”
Kinetic modelling approaches to in vivo imaging (2001, neutral): “The pseudocolour images graphically depict the evolving solutions of this model for Ca and Ins(1,4,5)P 3 at more than 7,000 locations, each 1.”
Growing dendrites and axons differ in their reliance on the secretory pathway. (2007, background): “FRAP monitors the traffic of molecules into a selected area that has previously been photobleached (Lippincott-Schwartz et al., 2001).”
The Open Microscopy Environment (OME) Data Model and XML file: open tools for informatics and quantitative analysis in biological imaging (2005, background): “This is especially true for fluorescence or bioluminescence, where the signal recorded at any point in the sample gives a direct measure of the number of target molecules in the sample [1-4].”
Luminescent nanomaterials for biological labelling (2005, methodology): “GFPs have been used as tools in numerous applications, including as biological labels to track and quantify individual or multiple protein species [46], as probes to monitor protein– protein interactions [45, 47, 48], and as biosensors to describe biological events and signals [45, 47].”