A Prospective Randomized Trial Comparing Percutaneous Local Ablative Therapy and Partial Hepatectomy for Small Hepatocellular Carcinoma

By Minshan Chen, Jin-qing Li, Yun Zheng, R. Guo, Hui-hong Liang, Ya-qi Zhang, Xiaojun Lin, W. Lau. Annals of Surgery, 2006

1,422 citations recorded by the source corpus.

Subfields: Epidemiology, Hepatology, Surgery

View Paper: https://www.semanticscholar.org/paper/103e8ad693af413cfc22d32c3ebb73a1952ef5c0

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Epidemiology

1. J. Llovet
2. Jordi Bruix1 , 2
3. V. Mazzaferro
4. Amit G. Singal
5. Peter R. Galle
6. Andrew X. Zhu
7. Riccardo Lencioni
8. M. Kudo

In Hepatology

1. J. Llovet
2. Jordi Bruix1 , 2
3. Riccardo Lencioni
4. V. Mazzaferro
5. Amit G. Singal
6. Andrew X. Zhu
7. Peter R. Galle
8. T. de Baère

In Surgery

1. Jordi Bruix1 , 2
2. J. Llovet

Citations in the corpus

• Tremelimumab in combination with ablation in patients with advanced hepatocellular carcinoma (2016, positive): “Ablation - by means of alcohol, radiofrequency, microwave or cryoablation - is considered a curative alternative to surgical resection [17, 18].”
• EASL-EORTC clinical practice guidelines: management of hepatocellular carcinoma. (2012, result): “Two RCT have been reported with opposite results [272,273].”
• Global trends in hepatocellular carcinoma epidemiology: implications for screening, prevention and therapy (2023, background): “For HCC >3 cm in diameter, surgical resection can have higher complication rates, but ablation is associated with lower objective response rates (ORRs), RFS and OS 207–209 .”
• EASL-EORTC clinical practice guidelines: management of hepatocellular carcinoma. (2012, result): “Two RCT have been reported with opposite results [272,273].”
• Hepatocellular carcinoma: a global view (2010, result): “Subsequent studies, including two further randomized controlled trials, showed that RFA has similar efficacy to surgical resection in the treatment of early-stage HCCs, and is associated with lower complication rates and costs than resection ( Table 3 )”
• Asian Pacific Association for the Study of the Liver consensus recommendations on hepatocellular carcinoma (2010, background): “Another trial showed that overall survival and disease-free survival rates were not statistically different between RFA and resection, but complications were more frequent and severe after surgery [309].”