Prefrontal cortex dysfunction during working memory performance in schizophrenia: reconciling discrepant findings.

By Dara S. Manoach. Schizophrenia Research, 2003

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Temporality and psychopathology (2013, background): “46 A number of studies have shown marked deficits of working memory and executive control functions which manifest themselves as formal thought disorders (Vogeley et al. 1999; Manoach 2003).”
Phenomenology and Psychopathology (2010, background): “Neuropsychological evidence links these analyses to disturbances of working memory and of executive control functions mainly located in the prefrontal cortex (Fuster 1997; Harrington et al. 1998; Manoach 2003), in particular, with the timing or sequencing component of mental activity.”
Beyond hypofrontality: A quantitative meta‐analysis of functional neuroimaging studies of working memory in schizophrenia (2005, background): “…signal is maximal at or around the working memory capacity of each individual and decreases when subjects must process sub- or suprathreshold amounts of information, suggesting that each individual should be imaged while performing a working memory task at his or her own capacity [Manoach, 2003].”
Sleep-dependent memory consolidation (2005, background): “For example, it has been suggested that cognitive deficits in people with schizophrenia arise in part from an inability to automate simple procedural learnin”