Quantitative and reproducible murine model of excisional wound healing

By R. Galiano, J. Michaels, V, Michael Dobryansky, J. Levine, G. Gurtner. Wound Repair and Regeneration, 2004

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Wound Healing: A Cellular Perspective. (2019, background): “When murine models for wound healing are employed, there is an emphasis on application of silicone stents around the excised skin, which prevents contraction and allows for healing through granulation tissue formation and re-epithelialization (132).”
Paracrine Factors of Mesenchymal Stem Cells Recruit Macrophages and Endothelial Lineage Cells and Enhance Wound Healing (2008, methodology): “The animals were randomly divided into three groups and the excisional wound splinting model was generated as described previously [21].”
Epithelialization in Wound Healing: A Comprehensive Review (2014, background): “This model minimizes contraction, a mechanism by which murine wounds mostly heal, and allows wound healing to occur primarily through the processes of granulation and re-epithelialization.(158,167) However, differences in skin composition (e.”