Integer Programming: the Global Impact

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Best Subset Selection via a Modern Optimization Lens (2015, background): “Each version released in these years produced a speed improvement on the previous version, leading to a total speedup factor of more than 29,000 between the first and last version tested [see Bixby (2012), Nemhauser (2013) for details].”
Optimal classification trees (2017, background): “The total speedup factor was measured to be more than 29,000 between these versions (Bixby 2012; Nemhauser 2013).”
Optimal trees for prediction and prescription (2018, background): “The total speedup factor was measured to be more than 29,000 between these versions [22, 92].”