Nanodrug Delivery: Is the Enhanced Permeability and Retention Effect Sufficient for Curing Cancer?

By Yuko Nakamura, A. Mochida, Peter L. Choyke, Hisataka Kobayashi. Bioconjugate chemistry, 2016

938 citations recorded by the source corpus.

Subfields: Biomaterials, Biomedical Engineering, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/0f8543a384865e5dce295668f61eca3e81f3261a

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In Biomedical Engineering

1. Ali Kosar

Citations in the corpus

• Transition Metal Complexes and Photodynamic Therapy from a Tumor-Centered Approach: Challenges, Opportunities, and Highlights from the Development of TLD1433 (2018, neutral): “25 In this case, photosensitizers are carried by nanoparticles or liposomes that penetrate the leaky vasculature of tumors due to their compatible size.”
• Therapeutic Nanoparticles and Their Targeted Delivery Applications (2020, background): “Therefore, nanoparticles with appropriate sizes can reach to the tumor area relatively easily and accumulate for a longer time, which is known as the enhanced permeability and retention (EPR) effect [10,11].”
• Smart nanocarrier-based drug delivery systems for cancer therapy and toxicity studies: A review (2018, background): “Both the phenomena are collectively known as the EPR effect [171].”