DNA-programmable nanoparticle crystallization

By Sung Yong Park, Abigail K. R. Lytton-Jean, Byeongdu Lee, S. Weigand, George C. Schatz, Chad A. Mirkin. Nature, 2008

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From Molecular to Macroscopic via the Rational Design of a Self-Assembled 3D DNA Crystal (2009, neutral): “Pictures of the rhombohedral crystals are shown in Figure 1b. Unlike self-assembled 2D crystals, typically a few microns in extent,5 or 3D DNA-nanoparticle crystals,6,7 these self-assembled 3D crystals are macroscopic objects, exceeding 250 microns in dimension.”
X-ray scattering characterisation of nanoparticles (2015, background): “showed SAXS patterns for both fcc and bcc AuDNA structures.[359] The structure was controlled through the selectivity of the DNA linker molecules.”
Enzyme-responsive nanoparticles for drug release and diagnostics. (2012, background): “For instance, when nanoparticles are decorated with biomolecules such as peptides or oligonucleotides, their assembly and dispersion can be programmed, which results in different physical properties of the nanoparticle collectives compared to the initial building blocks [14, 15].”
Design principles for self-assembly with short-range interactions (2011, background): “5kBT can be introduced using a complementary DNA strand (39, 40).”