Brain glucose metabolism in the early and specific diagnosis of Alzheimer’s disease

By Lisa Mosconi. European Journal of Nuclear Medicine and Molecular Imaging, 2005

893 citations recorded by the source corpus.

Subfields: Physiology, Psychiatry and Mental health, Radiology, Nuclear Medicine and Imaging

View Paper: https://www.semanticscholar.org/paper/0f6e3c5452bf9ed6130ad232dfcfebaac620a3ad

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Citations in the corpus

The amyloid β-peptide is imported into mitochondria via the TOM import machinery and localized to mitochondrial cristae (2008, background): “It is noteworthy that in AD at an early stage there is already a reduction in the number of mitochondria (14), the brain glucose metabolism is decreased (15), and the activities of both tricarboxylic acid cycle enzymes (16) and cytochrome c oxidase (COX) are reduced (17–20).”
Hierarchical feature representation and multimodal fusion with deep learning for AD/MCI diagnosis (2014, neutral): “Braak, 1991; Burton et al., 2009; Desikan et al., 2009; Devanand et al., 2007; Ewers et al., 2012; Lee et al., 2006; Mosconi, 2005; Visser et al., 2002; Walhovd et al., 2010), superior/medial frontal gyrus (Johnson et al., 2005), precentral/postcentral gyrus (Belleville et al., 2011), precuneus…”
Multicenter Standardized 18F-FDG PET Diagnosis of Mild Cognitive Impairment, Alzheimer's Disease, and Other Dementias (2008, background): “Education* (y) 15 (3), 10–18 13 (4), 10–18 10 (4), 5–18 11 (5), 3–18 12 (4), 4–18”
Latent feature representation with stacked auto-encoder for AD/MCI diagnosis (2013, background): “…et al. 2013; Yao et al. 2012), superior parietal lobule, precuneus, cuneus (Bokde et al. 2006; Singh et al. 2006; Davatzikos et al. 2011), cingulate region (Mosconi 2005), anterior limb of internal capsule (Zhang et al. 2009), caudate nucleus (Dai et al. 2009), fornix (Copenhaver et al. 2006).”
Ways toward an early diagnosis in Alzheimer's disease: The Alzheimer's Disease Neuroimaging Initiative (ADNI) (2005, neutral): “Although there is a certain overlap of the hypometaolic regions found in AD with those found in other forms f dementia, the patterns of metabolic abnormalities are ufficiently different to distinguish AD from other demenias [53].”
Decoding Alzheimer's disease from perturbed cerebral glucose metabolism: implications for diagnostic and therapeutic strategies. (2013, methodology): “neocortical regions like parietal, temporal, and finally frontal cortex (Jauhiainen et al., 2008; Mosconi, 2005), which may reflect different susceptibilities of brain regions to hypometabolism in MCI or AD brain.”