Alternatives to antibiotics-a pipeline portfolio review.
By L. Czaplewski, R. Bax, Martha R. J. Clokie, M. Dawson, H. Fairhead, V. Fischetti, S. Foster, B. Gilmore, Robert E. W. Hancock, D. Harper and 14 more. Lancet. Infectious Diseases (Print), 2016
717 citations recorded by the source corpus.
Subfields: Biotechnology, Ecology, Molecular Medicine
View Paper: https://www.semanticscholar.org/paper/0ebe25a0894080994860f7239c614c9c6ec7e13d
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Citations in the corpus
- Antimicrobial Peptides: An Emerging Category of Therapeutic Agents (2016, background): “…as mode of action, intensive nonclinical and clinical research is now invested into identification of new and non-conventional anti-infective therapies, including adjunctive or preventive approaches such as antibodies targeting a virulence factor, probiotics, and vaccines (Czaplewski et al., 2016).”
- Antimicrobial photodynamic inactivation: a bright new technique to kill resistant microbes (2016, background): “Since the antibiotic era is now widely supposed to be on the verge of ending [46], and the prospect of discovering novel classes of antibiotics is considered to be rather low [47] (although incremental improvements are still being made [48]), it is necessary to discover alternative antimicrobial tec”
- Clinical and Pathophysiological Overview of Acinetobacter Infections: a Century of Challenges (2016, neutral): “applications) without substantial further scientific advancements (287).”
- Antimicrobial peptides: Application informed by evolution (2020, background): “The diversity and potency of AMPs make them attractive targets for development as antimicrobial drugs (2) and surface antiseptics (3), and dozens of AMPs are currently being evaluated in clinical trials (4).”
- The One Health Concept: 10 Years Old and a Long Road Ahead (2018, background): “Likewise, just as the specter of the postantibiotic era appears before us (56), research into alternative anti-infectives has become an international priority, once again backed by the WHO, who recommends a global action plan based on “One Health” principles (57).”
- Antimicrobial photodynamic therapy – what we know and what we don’t (2018, background): “Consequently, in a recent review in Lancet Infectious Diseases, several alternatives for antibiotics were summarized and discussed from a medical and economical point of view (Czaplewski et al. 2016).”