Classification of small molecule protein kinase inhibitors based upon the structures of their drug-enzyme complexes.
By R. Roskoski. 2016
734 citations recorded by the source corpus.
Subfields: Genetics, Molecular Biology, Pathology and Forensic Medicine
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In Pathology and Forensic Medicine
Citations in the corpus
- Kinase-targeted cancer therapies: progress, challenges and future directions (2018, background): “Finally, small molecules that form covalent adducts with the target enzyme were recently termed as covalent inhibitors [94].”
- DOCKSTRING: Easy Molecular Docking Yields Better Benchmarks for Ligand Design (2021, neutral): “101 In contrast, the top de novo molecule did not appear to interact with the hinge according to Autodock Vina.”