Mortality and prehospital thrombolysis for acute myocardial infarction: A meta-analysis.

By L. Morrison, P. Verbeek, Andrew McDonald, Bruce V Sawadsky, D. Cook. Journal of the American Medical Association (JAMA), 2000

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2017 ESC Guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation. (2017, methodology): “When fibrinolysis is the reperfusion strategy, it is recommended to initiate this treatment as soon as possible after STEMI diagnosis, preferably in the pre-hospital setting.(96,98,123,222) I A”
Management of acute myocardial infarction in patients presenting with persistent ST-segment elevation: the Task Force on the Management of ST-Segment Elevation Acute Myocardial Infarction of the European Society of Cardiology. (2008, background): “6000 patients were randomized to pre-hospital or in-hospital fibrinolysis has shown a significant reduction (17%) in early mortality with pre-hospital treatment.(63) In a meta-analysis of 22 trials,(64) a much larger mortality reduction .”
2013 ACCF/AHA guideline for the management of ST-elevation myocardial infarction: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. (2013, methodology): “A meta-analysis of 6 higherquality RCTs revealed an approximately 60-minute reduction in time from symptom onset to delivery of fibrinolytic therapy with prehospital versus hospital-based administration, with a corresponding 17% reduction in risk of all-cause hospital mortality.(154) Analysis of a s”