Cdks, cyclins and CKIs: roles beyond cell cycle regulation

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Lipid Peroxidation: Production, Metabolism, and Signaling Mechanisms of Malondialdehyde and 4-Hydroxy-2-Nonenal (2014, background): “Mario F. Muñoz was supported by Consejeria de Economı́a, Innovacion y Ciencia de la Junta de Andalucia (Spain) postdoctoral fellowship (P10-CTS-6494).”
Cyclin-dependent kinases (2014, background): “Since these pioneer studies conducted in the 1980s, the importance of CDKs acting as a major eukaryotic protein kinase family involved in the integration of extracellular and intracellular signals to modulate gene transcription and cell division has been clearly established [3-6].”
Doxorubicin—An Agent with Multiple Mechanisms of Anticancer Activity (2023, background): “Moreover, CHK2 phosphorylates TP53, a protein regarded as the guardian of the genome, which controls the expression of proapoptotic genes (including proapoptotic protein BAX) and inhibitors of antiapoptotic proteins (including phorbol-12-myristate-13-acetate-induced protein 1 (NOXA) and isoform 1 of”