An Overview of Plant Phenolic Compounds and Their Importance in Human Nutrition and Management of Type 2 Diabetes
By Derong Lin, Mengshi Xiao, Jingjing Zhao, Zhuohao Li, B. Xing, Xindan Li, Maozhu Kong, Liangyu Li, Qing Zhang, Yaowen Liu and 4 more. Molecules, 2016
953 citations recorded by the source corpus.
In this paper, the biosynthesis process of phenolic compounds in plants is summarized, which include the shikimate, pentose phosphate and phenylpropanoid pathways. Plant phenolic compounds can act as antioxidants, structural polymers (lignin), attractants (flavonoids and carotenoids), UV screens (flavonoids), signal compounds (salicylic acid and flavonoids) and defense response chemicals (tannins and phytoalexins). From a human physiological standpoint, phenolic compounds are vital in defense responses, such as anti-aging, anti-inflammatory, antioxidant and anti-proliferative activities. Therefore, it is beneficial to eat such plant foods that have a high antioxidant compound content, which will cut down the incidence of certain chronic diseases, for instance diabetes, cancers and cardiovascular diseases, through the management of oxidative stress. Furthermore, berries and other fruits with low-amylase and high-glucosidase inhibitory activities could be regarded as candidate food items in the control of the early stages of hyperglycemia associated with type 2 diabetes.
Subfields: Biochemistry, Complementary and alternative medicine, Endocrinology, Diabetes and Metabolism
View Paper: https://www.semanticscholar.org/paper/0c5e713dbe64d16094c50751140a56f6ecc45239
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Citations in the corpus
- Lactic Fermented Fruit or Vegetable Juices: Past, Present and Future (2020, neutral): “Phenolic compounds are considered as good regulators of carbohydrate metabolism through the inhibition activities of α -glucosidase and α -amylase due to their chelating, structure altering, and biological function-limiting capacity to the enzymes [134,135].”
- Role of Phenolic Compounds in Human Disease: Current Knowledge and Future Prospects (2021, background): “Reactive oxygen (ROS) and reactive nitrogen (RNS) species are highly reactive oxidized molecules, including superoxide, peroxide, singlet oxygen, hydroxyl radical, nitric oxide (NO), and peroxynitrite (OONO−), that are constantly produced under normal cellular conditions, such as during homeostasis,”