Early detection of acute renal failure by serum cystatin C.

By S. Herget-Rosenthal, G. Marggraf, J. Hüsing, F. Göring, F. Pietruck, O. Janssen, T. Philipp, A. Kribben. Kidney International, 2004

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Subfields: Nephrology

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The RIFLE criteria and mortality in acute kidney injury: A systematic review. (2008, background): “The limitations of these current criteria may be helped by the use of emerging biomarkers for AKI, such as cystatin C and neutrophil gelatinase-associated lipocalin.(25,35) These can be used to further refine the criteria, or be used in conjunction with traditional AKI markers, such as creatinine an”
Cardiorenal syndrome. (2008, positive): “Cystatin C predicts AKI and the requirement for renal replacement therapy earlier than creatinine (47).”
RIFLE criteria for acute kidney injury are associated with hospital mortality in critically ill patients: a cohort analysis (2006, methodology): “Although, Herget-Rosenthal and colleagues have also described the progression of acute kidney injury in a selected cohort of 85 ICU patients [20], this is to our knowledge the first time that the progression of acute kidney injury has been examined in a large dataset of general ICU patients.”