Semi-synthetic artemisinin: a model for the use of synthetic biology in pharmaceutical development

By C. Paddon, Jay D. Keasling. Nature Reviews Microbiology, 2014

626 citations recorded by the source corpus.

Subfields: Computational Theory and Mathematics, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/0afaf40f75bac0576db1674571f92c38570bae81

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In Molecular Biology

1. Maria V. Filsinger Interrante
2. Christina D. Smolke
3. Kate Thodey
4. Stephanie Galanie
5. Isis J Trenchard

Citations in the corpus

• Discovery and resupply of pharmacologically active plant-derived natural products: A review (2015, positive): “…funded by a five year grant from the Bill & Melinda Gates Foundation, and involved the University of California, Berkeley, USA, the synthetic biology inventor Amyris Inc., and the non-profit pharmaceutical company One World Health (now PATH's Drug Development Program) (Paddon and Keasling, 2014).”
• Complete biosynthesis of opioids in yeast (2015, positive): “Semi-synthetic production of artemisinin has now reached the market, meeting up to one-third of global need (8, 9).”