Total-Body PET: Maximizing Sensitivity to Create New Opportunities for Clinical Research and Patient Care

By S. Cherry, T. Jones, J. Karp, Jinyi Qi, William W. Moses, R. Badawi. Journal of Nuclear Medicine, 2018

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Redefining Radiology: A Review of Artificial Intelligence Integration in Medical Imaging (2023, background): “Functional imaging techniques such as PET, which is uniquely characterised by its use of radiolabelled biochemical substances, and Single-Photon Emission Computed Tomography (SPECT), employing gamma-emitting radionuclides to trace biological processes, illuminated metabolic and biological processes,”
Performance Evaluation of the uEXPLORER Total-Body PET/CT Scanner Based on NEMA NU 2-2018 with Additional Tests to Characterize PET Scanners with a Long Axial Field of View (2020, background): “The sensitivity gain offered by long-AFOV PET scanners opens up new possibilities for numerous research and clinical applications, including PET imaging with a much lower injected dose, late-timepoint imaging, very fast imaging, and simultaneous total-body dynamic PET image acquisition (8,9).”
First Human Imaging Studies with the EXPLORER Total-Body PET Scanner* (2019, background): “These gains could be used either to (1) deliver enhanced image quality, (2) reduce scan time, (3) increase the time window after injection when scanning is possible, (4) reduce dose, or some combination of these.”