Human Monkeypox
By A. McCollum, I. Damon. Clinical Infectious Diseases, 2013
691 citations recorded by the source corpus.
Human monkeypox is a zoonotic Orthopoxvirus with a presentation similar to smallpox. Clinical differentiation of the disease from smallpox and varicella is difficult. Laboratory diagnostics are principal components to identification and surveillance of disease, and new tests are needed for a more precise and rapid diagnosis. The majority of human infections occur in Central Africa, where surveillance in rural areas with poor infrastructure is difficult but can be accomplished with evidence-guided tools and educational materials to inform public health workers of important principles. Contemporary epidemiological studies are needed now that populations do not receive routine smallpox vaccination. New therapeutics and vaccines offer hope for the treatment and prevention of monkeypox; however, more research must be done before they are ready to be deployed in an endemic setting. There is a need for more research in the epidemiology, ecology, and biology of the virus in endemic areas to better understand and prevent human infections.
Subfields: Epidemiology, Molecular Biology, Virology
View Paper: https://www.semanticscholar.org/paper/0a0fbb58f15f5e90591a20535d522ff3c305df3d
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- A. Yinka-Ogunleye
- A. McCollum
- O. Aruna
- M. Dalhat
- D. Ogoina
- Y. Disu
- Ibrahim Mamadu
- Afolabi Akinpelu
Citations in the corpus
- Outbreak of human monkeypox in Nigeria in 2017–18: a clinical and epidemiological report (2019, background): “1,7 8 Two distinct clades of monkeypox virus were responsible for the outbreaks in central and west Africa: the Congo Basin clade and the west African clade, respectively.”
- Clinical features and management of human monkeypox: a retrospective observational study in the UK (2022, neutral): “30 This hypothesis was further supported by negative orthopoxvirus IgG and IgM tests on serum taken at hospital admission from patient 7 (2021), 20 days after symptom onset in patient 5 (index case) and 13 days before she became symptomatic.”