A colorimetric gold nanoparticle sensor to interrogate biomolecular interactions in real time on a surface.

By N. Nath, A. Chilkoti. Analytical Chemistry, 2002

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Nanobiosensors based on localized surface plasmon resonance for biomarker detection (2012, background): “In one of these examples [51], biotin was attached through a linker to gold nanospheres that were previously immobilized onto a glass substrate.”
Optical biosensors based on ZnO nanostructures: advantages and perspectives. A review (2016, background): “The surface effects in nanostructures are caused by their low size, surface structure, charge, wettability and high surface-to-volume ratio impose the challenges for biosensing applications [3-28].”
Nanobiosensors: Concepts and Variations (2013, result): “Due to the phenomenon of surface plasmon resonance, a nanobiosensor is better equipped to detect the minutest interacting phenomenon, which enables a far greater and much reliable degree of estimation of biological interactions through a nanobiosensor in comparison with a biosensor [26–28].”