Carbon Dots for Optical Imaging in vivo

By Sheng-Tao Yang, Li Cao, P. Luo, Fushen Lu, Xin Wang, Haifang Wang, Mohammed Meziani, Yuanfang Liu, Gang Qi, Ya‐Ping Sun. Journal of the American Chemical Society, 2009

1,376 citations recorded by the source corpus.

It was found and recently reported that small carbon nanoparticles can be surface-passivated by organic or biomolecules to become strongly fluorescent. These fluorescent carbon nanoparticles, dubbed "carbon dots", can be successfully used for in vitro cell imaging with both one- and two-photon excitations, as already demonstrated in the literature. Here we report the first study using carbon dots for optical imaging in live mice. The results suggest that the carbon dots remain strongly fluorescent in vivo, which, coupled with their biocompatibility and nontoxic characteristics, might offer great potential for imaging and related biomedical applications.

Subfields: Materials Chemistry

View Paper: https://www.semanticscholar.org/paper/09b95ea2e06168962f360dbad65eb600d97df487

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In Materials Chemistry

1. K. Dimos
2. Abdullah M. Asiri
3. Xuping Sun
4. Xiaogang Qu
5. Jinsong Ren
6. Bailu Xu
7. Xiaohui Wang
8. Konggang Qu

Citations in the corpus

• Carbon Quantum Dots: Surface Passivation and Functionalization (2016, background): “Later on, Anilkumar’s team again grafted PEG1500N after thionyl chloride reaction and proceeded further in crosslinking the CQDs with dimethyl pimelimidate [143].”