A circadian gene expression atlas in mammals: Implications for biology and medicine

By Ray Zhang, Nicholas F. Lahens, Heather Ballance, Michael Hughes, John B. Hogenesch. Proceedings of the National Academy of Sciences of the United States of America, 2014

2,072 citations recorded by the source corpus.

Subfields: Applied Psychology, Endocrine and Autonomic Systems, Genetics

View Paper: https://www.semanticscholar.org/paper/096841f39dbaae4abad6939a2694eafef92ef80c

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Applied Psychology

1. J. Cade

In Endocrine and Autonomic Systems

1. Till Roenneberg
2. M. Merrow
3. Satchidananda Panda
4. S. Gill
5. Christoph Randler
6. K. Jankowski

In Genetics

1. Eran Segal

Citations in the corpus

• A smartphone app reveals erratic diurnal eating patterns in humans that can be modulated for health benefits (2015, background): “, 2009), and the targets of a large number of FDA approved drugs show circadian expression (Zhang et al., 2014).”
• SUPPA2: fast, accurate, and uncertainty-aware differential splicing analysis across multiple conditions (2018, positive): “full circadian cycles [40] (GSE54651) and performed a comparison with 50 events validated by RT-PCR [9] comparing samples CT28, CT40, and CT52 in cerebellum with the same circadian time points in liver (Additional file 2: Tables S8 and S9).”
• Gut microbiota induce IGF-1 and promote bone formation and growth (2016, background): “As with GH, liver Igf1 expression is circadian, and detection of differences may depend on sampling time (41).”
• Circadian Rhythm and Sleep Disruption: Causes, Metabolic Consequences and Countermeasures (2016, positive): “This is particularly pertinent given that most of the highestselling drugs target the products of rhythmically transcribed genes (78).”
• Microbiota Diurnal Rhythmicity Programs Host Transcriptome Oscillations. (2016, positive): “As a result, up to 20% of a tissue’s total transcriptome and up to 50% of all transcripts in the body consist of oscillating elements, which determine the diurnal pattern of cellular and organismal activity (Panda et al., 2002; Zhang et al., 2014).”
• The Circadian Clock and Human Health. (2016, background): “Since the clock regulates about half of the known targets of the best-selling drugs worldwide [118], side effects can be minimised while primary effects maximised by tuning the drug’s timing.”