Single-cell RNA-seq highlights intra-tumoral heterogeneity and malignant progression in pancreatic ductal adenocarcinoma
By Junya Peng, Bao-Fa Sun, Chuan-Yuan Chen, Jia‐Yi Zhou, Yu-Sheng Chen, Hao Chen, Lulu Liu, Dan Huang, Jialin Jiang, Guanshen Cui and 13 more. Cell Research, 2019
1,024 citations recorded by the source corpus.
Subfields: Cancer Research, Molecular Biology, Oncology
View Paper: https://www.semanticscholar.org/paper/090d1f9f8527392d9780e088d765ff1651478326
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In Molecular Biology
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- Spatially Informed Cell Type Deconvolution for Spatial Transcriptomics (2022, result): “…performance compared to the other methods in capturing the gross segregation of cancer and non-cancer regions, identifying two distinct cancer subregions, accurately localizing cell types and revealing a possible tumor microenvironment supporting tumor progression 54–57 (Supplementary Figs.”