PIN Proteins Perform a Rate-Limiting Function in Cellular Auxin Efflux

By J. Petrášek, J. Mravec, Rodolphe Bouchard, J. Blakeslee, M. Abas, Daniela Seifertová, J. Wiśniewska, Z. Tadele, M. Kubeš, Milada Čovanová and 12 more. Science, 2006

951 citations recorded by the source corpus.

Subfields: Molecular Biology, Plant Science

View Paper: https://www.semanticscholar.org/paper/0904a18fe064fe698394146eacf65efa78ff438c

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Molecular Biology

1. Yunde Zhao
2. T. Beeckman
3. René Benjamins
4. Ben Scheres
5. Jir□í Friml
6. Youfa Cheng
7. J. Petrášek
8. H. Fukaki

In Plant Science

1. Yunde Zhao
2. T. Beeckman
3. René Benjamins
4. Ben Scheres
5. Jir□í Friml
6. Youfa Cheng
7. J. Petrášek
8. H. Fukaki

Citations in the corpus

• Antagonistic regulation of PIN phosphorylation by PP2A and PINOID directs auxin flux. (2007, neutral): “*Correspondence: jifri@psb.ugent.be DOI 10.1016/j.cell.2007.07.033”
• Auxin: the looping star in plant development. (2008, background): “Hints toward the exact molecular function of PIN proteins came from experiments in which they represent the rate-limiting factor in the efflux of auxin as well as major determinants in providing directionality to polar auxin flow (91, 136).”
• Auxin control of root development. (2010, background): “…protein families that facilitate auxin influx (e.g., AUXIN RESISTANT1 [AUX1] and LIKE-AUX1 [LAX]) (Bennett et al. 1996; Swarup et al. 2001) and efflux (e.g., members of the P-GLYCOPROTEIN ABC transporter family [Geisler and Murphy 2006] and the PINFORMED [PIN] proteins [Petrasek et al. 2006]).”
• Auxin: a trigger for change in plant development. (2009, neutral): “Indeed, PIN proteins are capable of mediating auxin efflux from plant, mammalian, and yeast cells (Petrášek et al., 2006).”
• Auxin transport routes in plant development (2009, methodology): “The PIN1, PIN2, PIN3, PIN4 and PIN7 proteins, by contrast, are localized at the plasma membrane, where they act as auxin efflux carriers (Mravec et al., 2008; Petrásek et al., 2006).”
• A Role for Auxin in Flower Development (2007, background): “In addition to the dramatic gynoecium patterning defects observed in ettin-1, all other floral organs are misshapen in ett-1arf4 double mutants ( Pekker et al. 2005 ).”
• Signal integration in the control of shoot branching (2011, background): “In addition, the identification of the proteins responsible for auxin efflux from cell”
• The plant vascular system: evolution, development and functions. (2013, background): “PIN proteins act through asymmetric subcellular localization to direct routes of auxin flow through cells and tissues (Petrášek et al. 2006, Petrášek and Friml 2009).”
• Comprehending crystalline β-carotene accumulation by comparing engineered cell models and the natural carotenoid-rich system of citrus (2011, positive): “The synthetic auxins NAA and 2,4-D represent useful tools for single-cell-based auxin transport studies because of the distinct specificity of auxin influx and efflux carriers, particularly in tobacco cells (Delbarre et al., 1996; Petrášek et al., 2006).”
• Auxin in action: signalling, transport and the control of plant growth and development (2006, neutral): “org/servlets/TairObject?id=429341&type=gene">PIN7 — transport IA”