Vasoactive intestinal polypeptide mediates circadian rhythmicity and synchrony in mammalian clock neurons

By Sara J. Aton, C. Colwell, A. Harmar, J. Waschek, E. Herzog. Nature Neuroscience, 2005

812 citations recorded by the source corpus.

Subfields: Cognitive Neuroscience, Endocrine and Autonomic Systems, Physiology

View Paper: https://www.semanticscholar.org/paper/08bae2db3d8dcf0ec6bbb01d5afc4cb40c1617fc

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cognitive Neuroscience

1. J. Takahashi
2. Till Roenneberg
3. E. Arrigoni
4. J. Lipton
5. M. Merrow
6. T. Scammell

In Endocrine and Autonomic Systems

1. J. Takahashi
2. J. Lipton
3. T. Scammell
4. E. Arrigoni
5. Till Roenneberg
6. C. H. Ko
7. M. Merrow
8. Ethan D. Buhr

In Physiology

1. C. H. Ko
2. J. Takahashi
3. Till Roenneberg
4. Ethan D. Buhr
5. J. Lipton
6. M. Merrow

Citations in the corpus

• The Circadian Clock and Human Health. (2016, background): “Genetic ablation of neuropeptides such as VIP or its receptor, VPAC2, leads to arrhythmicity at the behavioural level despite many neurons remaining rhythmic (in the case of the VIP knockout [104,105]).”
• Neural Circuitry of Wakefulness and Sleep (2017, positive): “VIP neurons in the core may act as a prime coupling signal for the influence of other neuropeptides, including AVP and GRP (Aton et al., 2005; Maywood et al., 2011; Mieda et al., 2015).”
• Molecular components of the mammalian circadian clock. (2006, background): “agonist to VIP / SCN neurons restores rhythmicity to arrhythmic cells and entrains the cells to a common phase (Aton et al. 2005).”
• Suprachiasmatic Nucleus: Cell Autonomy and Network Properties (2010, background): “Neuronal firing rhythms in SCN slices from these mice are suppressed (142), even at a single cell level (100, 143, 182).”
• Molecular components of the Mammalian circadian clock. (2013, background): “agonist to VIP / SCN neurons restores rhythmicity to arrhythmic cells and entrains the cells to a common phase (Aton et al. 2005).”
• Micro-LED arrays: a tool for two-dimensional neuron stimulation (2008, background): “MEA technology is extensively used today to study the dynamic of interactions within neuron networks (Hofmann and Bading 2006), synaptic plasticity (Lante et al 2006), visual perception (Cang et al 2005) and the effects of pharmacological compounds and putative therapeutics (Aton et al 2005).”
• Intercellular coupling confers robustness against mutations in the SCN circadian clock network. (2007, background): “Uncoupling of SCN cellular oscillators has been demonstrated by mechanical dissociation into single cells (Welsh et al., 1995; Herzog et al., 1998) or in slice preparations using tetrodotoxin (Yamaguchi et al., 2003) or genetic disruption of VIP signaling (Aton et al., 2005; Maywood et al., 2006).”
• Physiology of circadian entrainment. (2010, background): “mechanisms proposed include NO and GABA neurotransmission (16, 29, 282, 283, 318, 471, 497) as signals that couple SCN cells and might relay photic phase-adjustment information from the retinorecipient SCN to the dorsal region.”