The modern molecular clock

By L. Bromham, David Penny. Nature reviews genetics, 2003

619 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/07e298aa4bc7299c0bfd8164d900b90ce80102a2

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In Genetics

In Molecular Biology

Citations in the corpus

The Patterns and Causes of Variation in Plant Nucleotide Substitution Rates (2011, background): “258 Gaut et al. Putting It All Together On the basis of population-genetics principles, we can ascribe differences in rates among lineages to one of three underlying causes (reviewed in Bromham & Penny 2003).”
As Time Goes by: A Simple Fool's Guide to Molecular Clock Approaches in Invertebrates* (2009, background): “Due to the fact that extrapolation has fewer constraints, it is inferior over interpolations and uncertainties will increase with the distance between the calibration point and the estimated event (Bromham and Penny 2003).”
On the instability and evolutionary age of deep-sea chemosynthetic communities (2013, background): “DNA repair mechanisms, and recombination rates (Bromham and Penny, 2003; Kumar, 2005).”
Atlantic reef fish biogeography and evolution (2007, background): “Although controversial (cf. Bromham & Penny, 2003; Pulquério & Nichols, 2007), molecular phylogenies can provide some idea of the age of cladogenic events through the use of ‘molecular clocks’ (Avise, 2000).”
Climate change drives speciation in the southern rock agama (Agama atra) in the Cape Floristic Region, South Africa (2009, neutral): “Given the criticisms associated with using a constant molecular clock (Bromham & Penny, 2003; Kumar, 2005), we examined whether a constant mutation rate could reasonably be applied to the data set.”
The emerging field of geogenomics: Constraining geological problems with genetic data (2014, background): “It is the responsibility of the researcher to fully report uncertainty associated with time estimates (Bromham and Penny, 2003; Graur and Martin, 2004; Parham, 2012).”
The Logic of Chance: The Nature and Origin of Biological Evolution (2011, background): “Although it has been repeatedly observed that the molecular clock is significantly overdispersed, such tests strongly suggest that the fraction of neutral mutations among the fixed ones is indeed substantial (Bromham and Penny, 2003; Novichkov, et al., 2004).”
Molecular taxonomy, origins and evolution of freshwater ascomycetes (2006, background): “361 Nonetheless, global environmental changes have left footprints in the DNA of living organisms from which the evolutionary history can be reliably inferred (Brohman and Penny, 2003).”
The ranking of fungi: a tribute to David L. Hawksworth on his 70th birthday (2017, background): “Molecular clock studies are becoming a universal tool to place evolutionary events and explore new insights into genetic evolution (Bromham and Penny 2003; Kumar 2005; Vijaykrishna et al. 2006).”
Relaxed Phylogenetics and Dating with Confidence (2006, background): “Often paleontology or biogeography can provide a date for one or more points in a phylogeny, which are then used to “calibrate” the timescale for the rest of the phylogeny [3, 4 ].”