COVID-19 and the cardiovascular system
By Ying-Ying Zheng, Yi-tong Ma, Jin-Ying Zhang, Xiang Xie. Nature Reviews Cardiology, 2020
2,987 citations recorded by the source corpus.
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infects host cells through ACE2 receptors, leading to coronavirus disease (COVID-19)-related pneumonia, while also causing acute myocardial injury and chronic damage to the cardiovascular system. Therefore, particular attention should be given to cardiovascular protection during treatment for COVID-19.
Subfields: Infectious Diseases, Neurology
View Paper: https://www.semanticscholar.org/paper/0760193829395b1a7a8563c73950fb79797173b6
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Citations in the corpus
- A brief review of socio-economic and environmental impact of Covid-19 (2020, background): “…with a limited number of people benefiting from this scenario. c. Official regulations to avoid going out can be counterproductive for densely populated areas. d. Patients already suffering from chronic illnesses are at higher risk than healthy people (Giannis et al. 2020; Zheng et al. 2020). e.”
- Risk Factors Associated With Mortality Among Patients With COVID-19 in Intensive Care Units in Lombardy, Italy. (2020, neutral): “Length of mechanical ventilation, median (IQR), d 10 (6-16) 9 (5-15) 12 (7-18) 74 (73-78) <.”
- COVID-19 and the cardiovascular system: implications for risk assessment, diagnosis, and treatment options (2020, background): “Approximately 75% of patients in the early Chinese cohort received antiviral therapy.(6,32,43,115) The Italian recommendation is to commence treatment with antiviral therapy when COVID-19 is confirmed in patients with mild symptoms but not in a high mortality risk category or with moderate/severe si”
- COVID‐19 and Older Adults: What We Know (2020, background): “Many of these patients use ACE inhibitors and angiotensin-receptor blockers (ARBs) that upregulate the ACE-2 receptor.(14) Thus it is hypothesized that older individuals with such comorbidities may have an elevated risk of and experience a more severe course of infection with SARS-CoV-2.”
- Kidney disease is associated with in-hospital death of patients with COVID-19 (2020, background): “24 These potentially harmful effects may account for the low proportion of renin-angiotensin-aldosterone system inhibitors used by physicians in our cohort, especially in patients with AKI who had higher level of creatinine on admission.”
- Cardiovascular Considerations for Patients, Health Care Workers, and Health Systems During the COVID-19 Pandemic (2020, positive): “As theACE2 receptor is themechanismofentry for SARS-CoV2, some data suggest that ACE inhibitors and angiotensin receptor blockers (ARBs) may up-regulate ACE2, thereby increasing susceptibility to the virus (Figure 1) (5).”
- Automated medical diagnosis of COVID-19 through EfficientNet convolutional neural network (2020, background): “The first case of infection by coronavirus has been reported in December 2019 at Wuhan, China [3].”