Clinical Pharmacogenetics Implementation Consortium Guidelines for Cytochrome P450 2D6 Genotype and Codeine Therapy: 2014 Update

By K. Crews, A. Gaedigk, H. M. Dunnenberger, J. Leeder, T. Klein, K. Caudle, Cyrine E. Haidar, D. Shen, J. Callaghan, S. Sadhasivam and 3 more. Clinical pharmacology and therapy, 2014

622 citations recorded by the source corpus.

Subfields: Anesthesiology and Pain Medicine, Oncology, Pharmacology

View Paper: https://www.semanticscholar.org/paper/0748d4049dfd0f696468dc9897a5777fcdf64644

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1. Brian L. Browning
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5. Xiaowen Tian
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Citations in the corpus

• Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program (2019, background): “One such region is around the CYP2D6 gene, which encodes an enzyme that metabolizes approximately 25% of prescription drugs and the activity of which varies substantially among individuals 43–45 .”