A simple model of backbone flexibility improves modeling of side-chain conformational variability.

By Gregory D. Friedland, A. Linares, Colin A. Smith, Tanja Kortemme. 2008

82 citations recorded by the source corpus.

Subfields: Materials Chemistry, Molecular Biology

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Materials Chemistry

1. Tanja Kortemme
2. Colin A. Smith
3. David Baker
4. I. Samish
5. Jeffrey J. Gray
6. Jens Meiler
7. Xingjie Pan
8. Alexander M. Sevy

In Molecular Biology

1. Tanja Kortemme
2. Colin A. Smith
3. David Baker
4. I. Samish
5. Jeffrey J. Gray
6. Jens Meiler
7. Xingjie Pan
8. Noah Ollikainen

Citations in the corpus

• A smoothed backbone-dependent rotamer library for proteins derived from adaptive kernel density estimates and regressions (2011, unknown): “Backbone flexibility is increasingly incorporated into comparative modeling and protein design (Friedland et al., 2008; Smith and Kortemme, 2008).”
• Predicting the Tolerated Sequences for Proteins and Protein Interfaces Using RosettaBackrub Flexible Backbone Design (2011, methodology): “Our protocol utilizes ‘‘backrub’’ conformational moves in Rosetta [31,32] inspired by observations of conformational heterogeneity in high-resolution crystal structures [33].”