Post-discharge persistent symptoms and health-related quality of life after hospitalization for COVID-19

By Eve Garrigues, P. Janvier, Y. Kherabi, A. Le Bot, A. Hamon, H. Gouze, Lucile Doucet, S. Berkani, Emma Oliosi, Élise Mallart and 7 more. Journal of Infection, 2020

883 citations recorded by the source corpus.

Objective To assess post-discharge persistent symptoms and health-related quality of life (HRQoL) of patients hospitalized in a COVID-19 ward unit more than 100 days after their admission. Methods All eligible patients were contacted by phone by trained physicians and were asked to answer to a dedicated questionnaire. Patients managed in hospital ward without needing intensive care were compared with those who were transferred in intensive care units (ICU). Results We included 120 patients after a mean (±SD) of 110.9 (±11.1) days following admission. The most frequently reported persistent symptoms were fatigue (55%), dyspnoea (42%), loss of memory (34%), concentration and sleep disorders (28% and 30.8%, respectively). Comparisons between ward- and ICU patients led to no statistically significant differences regarding those symptoms. In both group, EQ-5D (mobility, self-care, pain, anxiety or depression, usual activity) was altered with a slight difference in pain in the ICU group. Conclusion Most patients requiring hospitalization for COVID-19 still have persistent symptoms. While there were few differences between HRQoL between ward and ICU patients, our findings must be confirmed in larger cohorts, including more severe patients.

Subfields: Critical Care and Intensive Care Medicine, Epidemiology, Neurology

View Paper: https://www.semanticscholar.org/paper/0657bfef05f2aee94107972f4bcad289c26a7aea

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Citations in the corpus

More Than 50 Long-Term Effects of COVID-19: A Systematic Review and Meta-Analysis (2021, neutral): “5 (19-84) 63 Fatigue, dyspnea, joint pain, chest pain, cough, anosmia, Sicca syndrome, Rhinitis, red eyes, dysgeusia, headache, sputum, lack of appetite, sore throat, vertigo, myalgia, diarrhea.”
Symptoms, complications and management of long COVID: a review (2021, background): “In a study that included individuals who regularly engaged in sports before hospitalisation for COVID-19 (details of the sporting activities were not given), 72% (28/39) were able to resume physical activity after three months, and nearly half of those were only able to do so at lower intensity.(20)”
Fatigue and cognitive impairment in Post-COVID-19 Syndrome: A systematic review and meta-analysis (2021, neutral): “…QOL using the European Quality of Life 5 dimension 5 levels (EQ-5D-5L) scale (Wong et al., 2020; PHOSPCOVID Collaborative Group et al., 2021; Garrigues et al., 2020; Johnsen et al., 2021; Miskowiak et al., 2021; Munblit et al., 2021), four used the EQ-5D-3L scale, (Huang et al., 2021; Todt…”