Pathogenicity and transmissibility of 2019-nCoV—A quick overview and comparison with other emerging viruses
By Jieliang Chen. Microbes and infection, 2020
729 citations recorded by the source corpus.
A zoonotic coronavirus, tentatively labeled as 2019-nCoV by the World Health Organization (WHO), has been identified as the causative agent of the viral pneumonia outbreak in Wuhan, China, at the end of 2019. Although 2019-nCoV can cause a severe respiratory illness like SARS and MERS, evidence from clinics suggested that 2019-nCoV is generally less pathogenic than SARS-CoV, and much less than MERS-CoV. The transmissibility of 2019-nCoV is still debated and needs to be further assessed. To avoid the 2019-nCoV outbreak turning into an epidemic or even a pandemic and to minimize the mortality rate, China activated emergency response procedures, but much remains to be learned about the features of the virus to refine the risk assessment and response. Here, the current knowledge in 2019-nCoV pathogenicity and transmissibility is summarized in comparison with several commonly known emerging viruses, and information urgently needed for a better control of the disease is highlighted.
Subfields: Infectious Diseases, Modeling and Simulation
View Paper: https://www.semanticscholar.org/paper/062ebe3b2b3afae974390c14db53e427892fdf8d
How researchers see this paper
The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.
- J. Smulian
- J. Lednicky
- S. Rasmussen
- T. Wen
- Muhammad Sohail Zafar
- D. Jamieson
- Marziya Aftab
- Naseer Ahmed
Citations in the corpus
- Coronavirus Disease 2019 (COVID-19) and pregnancy: what obstetricians need to know (2020, background): “6 and 2e5, respectively.(42) Current estimates of R0 for SARS-CoV-2 places it at 2.”
- Fear and Practice Modifications among Dentists to Combat Novel Coronavirus Disease (COVID-19) Outbreak (2020, background): “Although the mortality associated with COVID-19 is low, it has a high spreading potential [12].”
- A systematic review of asymptomatic infections with COVID-19 (2020, neutral): “The incidence of asymptomatic infections in the children is lower than that of the whole population, we propose that it is related to the special immune response and ACE2 level in the children’s bodies.(14) According to these studies, the ability of asymptomatic infections to spread the virus is not”