A circadian clock in macrophages controls inflammatory immune responses

By Maren Keller, J. Mazuch, U. Abraham, G. Eom, E. Herzog, H. Volk, A. Kramer, B. Maier. Proceedings of the National Academy of Sciences of the United States of America, 2009

816 citations recorded by the source corpus.

Subfields: Endocrine and Autonomic Systems, Experimental and Cognitive Psychology, Physiology

View Paper: https://www.semanticscholar.org/paper/05bebe3c2b180de8f4328ce16f5b78f7b83a8010

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Endocrine and Autonomic Systems

1. Björn H. Rasch
2. Jan Born

In Experimental and Cognitive Psychology

1. Björn H. Rasch
2. Jan Born
3. Luciana Besedovsky
4. T. Lange

In Physiology

1. Eran Segal
2. Luciana Besedovsky
3. T. Lange
4. Eran Elinav

Citations in the corpus

• Transkingdom control of microbiota diurnal oscillations promotes metabolic homeostasis. (2014, background): “…many biological processes, ranging from metabolism and behavior to immunity, and helps to synchronize these processes to diurnal fluctuations in environmental conditions (Asher et al., 2010; Gerhart-Hines et al., 2013; Keller et al., 2009; Nguyen et al., 2013; Silver et al., 2012; Yu et al., 2013).”
• Sleep and immune function (2011, background): “Peaks of pro-inflammatory and/or Th1 cytokines during the rest period have been observed, often during the early slow wave sleep (SWS)-dominated portion of sleep, in humans as well as in animals on the mRNA and protein level in different tissues including the brain [52, 69], adipose tissue [52] and ”
• The nuclear receptor REV-ERBα mediates circadian regulation of innate immunity through selective regulation of inflammatory cytokines (2011, background): “vehicle-treated animals showed no significant time-of-day differences, and TNF-α, which has previously been reported to be rhythmic in cultured macrophages (6), showed no significant time-of-day differences in vivo (Fig.”
• About sleep's role in memory. (2013, background): “In combination, these data support the view that sleep favors an accumulation of T cells in lymph nodes, and there might be a parallel effect on APC migration (307, 627).”