Alternans and spiral breakup in a human ventricular tissue model.

By K. T. Tusscher, A. Panfilov. American Journal of Physiology. Heart and Circulatory Physiology, 2006

1,163 citations recorded by the source corpus.

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A Novel Computational Model of the Human Ventricular Action Potential and Ca Transient (2009, methodology): “Among these, the Panfilov group has comprehensively modeled the individual currents generating an AP, with APD and conduction velocity restitution properties in agreement with experimental measurements (TNNP04 and TP06) [8,10].”
Simulation of the Undiseased Human Cardiac Ventricular Action Potential: Model Formulation and Experimental Validation (2011, positive): “Rate dependence in the TP model[9] is less [Na]i dependent because, as Grandi discussed[10], IKs is exaggerated.”