Can dietary ginger (Zingiber officinale) alter biochemical and immunological parameters and gene expression related to growth, immunity and antioxidant system in zebrafish (Danio rerio)?
By E. Ahmadifar, N. Sheikhzadeh, Kambiz Roshanaei, Narges Dargahi, Caterina Faggio. Aquaculture, 2019
210 citations recorded by the source corpus.
Abstract Effects of the dietary ginger (Zingiber officinale) on growth, some immunological and biochemical parameters and gene expression related to growth, immunity and antioxidant systems in zebrafish were studied. Immune parameters such as immunoglobulin level, alternative complement activity, and lysozyme activity were significantly higher in treatment groups fed with 2% and 3% ginger than the control fish. Amylase activity also increased significantly in the same pattern as the immunological parameters. Catalase and lysozyme mRNA expression levels representatives of antioxidant and immune genes respectively, were up-regulated in the fish fed with 3% ginger. Conversely, expression of gene encoding ghrelin was down-regulated in all treatment groups compared with the control group. Present study suggests that powdered ginger especially at 3% might augment some immunological and biochemical responses as well as expression of genes relevant to antioxidant and immune systems in zebrafish.
Subfields: Aquatic Science, Immunology, Pharmacology
View Paper: https://www.semanticscholar.org/paper/0557bf887af464e255657bfa27b1a8324778527b
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In Aquatic Science
In Immunology
Citations in the corpus
- Oxidative Stress and Antioxidant Defense in Fish: The Implications of Probiotic, Prebiotic, and Synbiotics (2020, background): “In zebrafish, Danio rerio, dietary administration of a 2% or 3% of ginger significantly increased the immunoglobulin level, alternative complement activity, and lysozyme activity, suggesting the beneficial effects on immunological and antioxidant systems (Ahmadifar et al. 2019).”