The epidemiology of human papillomavirus infections.
By J. Baseman, L. Koutsky. Journal of Clinical Virology, 2005
1,089 citations recorded by the source corpus.
Infection with oncogenic human papillomavirus (HPV) types is a necessary cause of cervical cancer, the second most frequently occurring cancer in women worldwide. Rates of acquisition of HPV are high, particularly among sexually active young adults. Reported estimates of incident HPV infection among initially negative women have reached as high as 60% over a 5-year follow-up period. In this article, we review the epidemiology of HPV infection. In addition to estimates of disease frequency, we highlight risk factors for HPV infection, including the number of lifetime sex partners, which is the most salient risk factor. We discuss significant issues surrounding the natural history of HPV infection, including viral persistence versus clearance, immune response, development of lesions and development of cancer. Finally, we discuss strategies for preventing HPV infection.
Subfields: Epidemiology, Surgery
View Paper: https://www.semanticscholar.org/paper/054bf932b05d33d13c9e66df840a5a9145f997ce
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Citations in the corpus
- Chapter 6: Epidemiology and transmission dynamics of genital HPV infection. (2006, background): “The associations between numbers of new and recent sexual partners and likelihood of detecting HPV-DNA in female genital tract specimens are strong and consistent [18, 19 ].”
- Human papillomavirus molecular biology and disease association (2015, background): “5% [65] in adults to over 30% in schoolchildren has been reported [66].”
- The biology and life-cycle of human papillomaviruses. (2012, background): “Low-grade squamous intraepithelial lesions LSIL), where infectious particles are produced, are generally flat nd inconspicuous, and in most cases these will regress spontaeously within 18 months [4,46,47].”