Flexible near field wireless optoelectronics as subdermal implants for broad applications in optogenetics
By G. Shin, A. Gomez, R. Al-Hasani, Y. Jeong, Jeonghyun Kim, Zhaoqian Xie, Anthony R. Banks, Seung Min Lee, S. Han, C. Yoo and 26 more. Neuron, 2017
391 citations recorded by the source corpus.
Summary In vivo optogenetics provides unique, powerful capabilities in the dissection of neural circuits implicated in neuropsychiatric disorders. Conventional hardware for such studies, however, physically tethers the experimental animal to an external light source limiting the range of possible experiments. Emerging wireless options offer important capabilities that avoid some of these limitations, but the current size, bulk, weight, and wireless area of coverage is often disadvantageous. Here, we present a simple but powerful setup based on wireless, near-field power transfer and miniaturized, thin flexible optoelectronic implants, for complete optical control in a variety of behavioral paradigms. The devices combine subdermal magnetic coil antennas connected to microscale, injectable LEDs, with the ability to operate at wavelengths ranging from ultraviolet to blue, green/yellow, and red. An external loop antenna allows robust, straightforward application in a multitude of behavioral apparatuses. The result is a readily mass-producible, user-friendly technology with broad potential for optogenetics applications.
Subfields: Biomedical Engineering, Cellular and Molecular Neuroscience
View Paper: https://www.semanticscholar.org/paper/054590ffaa25ed8050d54c02e0a9e69275c08f40
How researchers see this paper
The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.
In Biomedical Engineering
- John A. Rogers
- Zhenan Bao
- Yonggang Huang
- S. Yun
- Nanshu Lu
- Dae-Hyeong Kim
- Hyun‐Joong Chung
- Kenneth D. Harris
In Cellular and Molecular Neuroscience
Citations in the corpus
- Battery-free, wireless sensors for full-body pressure and temperature mapping (2018, background): “The operating range depends on the sizes and numbers of reader antennas, the RF power supplied to them, the sizes of the sensor antennas, and their angular orientation relative to the reader (38).”
- Multifunctional materials for implantable and wearable photonic healthcare devices (2020, background): “, Springer Nature Limited, and with permission from reF.(22), Elsevier.”