Exosomes: Therapy delivery tools and biomarkers of diseases

By Lucio Barile, G. Vassalli. Pharmacology and Therapeutics, 2017

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Exosomes as a new frontier of cancer liquid biopsy (2022, background): “Given that exosomes are secreted by living cells, the specific contents in exosomes could reflect the pathophysiological state of their parental cells, which makes them useful biomarkers for dynamic monitoring of disease progression [42].”
Designer exosomes produced by implanted cells intracerebrally deliver therapeutic cargo for Parkinson’s disease treatment (2018, neutral): “Biodistribution analysis of exosomes previous reports that exosomes in the peripheral circulation are not exclusively found in the brain, but also accumulate in spleen and liver 37 , which clear most nanoparticulates 38 (Supplementary Fig.”
Engineering exosomes for targeted drug delivery (2021, background): “Although the use of exosomes as drug delivery vehicles is the topic of many review articles [19-23], here we focus on the engineering of exosomes for Ivyspring”
Effect of exosomal miRNA on cancer biology and clinical applications (2018, background): “As a consequence, exosomes always succeed, even though they sometimestake a longer path to reach their target [84].”