Dissociation of broadband high-frequency activity and neuronal firing in the neocortex

By M. Leszczyński, A. Barczak, Y. Kajikawa, István Ulbert, A. Falchier, I. Tal, Saskia Haegens, Lucia Melloni, Robert T. Knight, Charles E. Schroeder. 2019

Subfields: Cognitive Neuroscience, Neurology

Citations in the corpus

• Human intracranial correlates of dynamic coding in auditory working memory (2026, unknown): “A significant advantage intracranial recordings is that they provide clear access to > 70 Hz broadband high-frequency activity (HFA), which has been suggested to be a close correlate of local neuronal spiking (Ray et al., 2008; Leszczynski et al., 2020).”
• Distinct laminar origins of sensory-evoked high-gamma and low-frequency ECoG signals revealed by optogenetics (2026, unknown): “Previous efforts to identify the contributions of specific neural layers and sources to CSEPs have primarily relied on correlations between ECoG, intracortical LFP, and spiking in vivo (8, 14, 18) or using computational simulations (17, 42).”
• Neural correlates of perceptual consciousness from within: A narrative review of human intracranial research (2025, unknown): “…reflecting the firing rates of the population of neurons located near depth electrodes or beneath strip or grid electrodes ( Lachaux et al., 2012 ; Nir et al., 2007 ; Ray and Maunsell, 2011 ) or dendritic processes, depending on the depth at which it is recorded ( Leszczy ń ski et al., 2020 ).”
• Distinct laminar origins of high-gamma and low-frequency ECoG signals revealed by optogenetics (2025, unknown): “If different CSEP frequency bands map to specific layers and cellular signals, these distinct CSEP bands could be used as biomarkers of columnar processing steps, providing a powerful new approach to dissect cortical computations 14,18,26 .”
• Dynamic Causal Tractography Analysis of Auditory Descriptive Naming: An Intracranial Study of 106 Patients (2025, unknown): “…modulations of high-gamma amplitude, an outstanding summary measure of neural activation due to its strong correlation with increased neural firing rates (Ray et al., 2008; Leszczyński et al., 2020), hemodynamic responses (Scheeringa et al., 2011), and glucose metabolism (Nishida et al., 2008).”
• Naturalistic Audiovisual Illusions Reveal the Cortical Sites Involved in the Multisensory Processing of Speech (2025, unknown): “To compute the broadband high-frequency activity (HFA), which indexes local cortical activity (Crone et al. 1998; Ray et al. 2008; Leszczyński et al. 2020), we filtered the iEEG signal of each trial between 75 and 175 Hz in 10-Hz bands (4 th - order Butterworth filters), computed instantaneous…”
• The development of aperiodic neural activity in the human brain (2024, unknown): “https://doi.org/10.1038/s41562-025-02270-x maturation 33,39–44 . iEEG provides rich and novel measures of neuro-physiology including low-frequency periodic and aperiodic activity, and high-frequency broadband activity reflecting neuronal population activity 45–49 .”