Changes in Arterial Stiffness and Wave Reflection With Advancing Age in Healthy Men and Women: The Framingham Heart Study

By Gary F. Mitchell, H. Parise, Emelia J. Benjamin, Martin G. Larson, M. Keyes, J. Vita, Ramachandran S. Vasan, Daniel Levy. HYPERTENSION, 2004

1,551 citations recorded by the source corpus.

Subfields: Cardiology and Cardiovascular Medicine

View Paper: https://www.semanticscholar.org/paper/02b98bd69d2a010d2e8bfbb62a9690c79b1f9f37

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In Cardiology and Cardiovascular Medicine

Citations in the corpus

Normal vascular aging: differential effects on wave reflection and aortic pulse wave velocity: the Anglo-Cardiff Collaborative Trial (ACCT). (2005, background): “In the present study, the relationship between age and AIx was clearly non-linear, with a greater age-related effect in younger individuals, supporting the findings of Mitchell et al. ( 12 ) and suggesting that AIx might be a more sensitive marker of arterial aging in younger individuals.”
Aging and arterial stiffness. (2010, background): “48 Pharmacological treatments include (1) antihypertensive treatment such as diuretics, α-blockers, angiotensinconverting enzyme (ACE) inhibitors, angiotensin-receptor blockers (ARB), and calcium-channel antagonists;49 (2) treatment of congestive heart failure, such as with ACE inhibitors, nitrates,”
Mechanical factors in arterial aging: a clinical perspective. (2007, methodology): “The modern approach (4,11,62) uses high-ﬁdelity tonometers to record noninvasively details of the radial and/or carotid pressure waveforms and mathematical processing to identify features of the wave, including the late systolic augmentation described by pioneers.”
Recommendations for Improving and Standardizing Vascular Research on Arterial Stiffness (2015, neutral): “Loss of impedance mismatch reduces the amount of wave reflection at the interface between aorta and proximal branch vessels and therefore increases transmission of excessive pulsatile energy into the periphery, where it may cause damage.(23,85,86) Increased aortic stiffness and excessive pressure pu”
Effects of central arterial aging on the structure and function of the peripheral vasculature: implications for end-organ damage. (2008, background): “1B) and may contribute to the association between aortic stiffening and diseases that share a microvascular etiology (62, 96).”