Subunit composition, distribution and function of GABA(A) receptor subtypes.
By W. Sieghart, G. Sperk. Current Topics in Medicinal Chemistry, 2002
955 citations recorded by the source corpus.
Subfields: Cellular and Molecular Neuroscience, Materials Chemistry, Molecular Biology
View Paper: https://www.semanticscholar.org/paper/0290697b9821bab2f27d243fb1c157d0612ef584
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In Cellular and Molecular Neuroscience
- Richard W. Olsen
- G. Homanics
- Arno Villringer
- M. Fanselow
- W. Sieghart
- Joseph E LeDoux
- Paul W. Frankland
- B. Bontempi
In Materials Chemistry
In Molecular Biology
Citations in the corpus
- Compensatory alteration of inhibitory synaptic circuits in cerebellum and thalamus of γ‐aminobutyric acid type A receptor α1 subunit knockout mice (2006, background): “…postsynaptic clustering -Aminobutyric acid type A (GABAA) receptors mediate the majority of inhibitory neurotransmission in the brain and represent major drug targets for the treatment of anxiety, sleep disorders, epilepsy, and muscle spasms (Mohler et al., 2002; Sieghart and Sperk, 2002).”
- Trace fear conditioning is enhanced in mice lacking the δ subunit of the GABAA receptor (2005, background): “These ligand-gated receptors are pentamers composed of various subunit combinations ( , , , , , , and ) that exhibit differential expression in the brain (Barnard et al. 1998; Sieghart and Sperk 2002).”
- Sex hormones affect neurotransmitters and shape the adult female brain during hormonal transition periods (2015, background): “Glutamate acts as the main excitatory neurotransmitter in the CNS and is a proximal regulator of cognitive domains such as learning and memory (Gazzaley et al., 1996; Foy et al., 1999; Riedel et al., 2003).”
- GABAA receptor trafficking and its role in the dynamic modulation of neuronal inhibition (2008, background): “The fast inhibitory actions of GABA are mediated by the activation of GABA A receptors (GABA A Rs) in the brai”
- International Union of Pharmacology. LXX. Subtypes of γ-Aminobutyric AcidA Receptors: Classification on the Basis of Subunit Composition, Pharmacology, and Function. Update (2008, background): “2 (Sieghart and Sperk, 2002).”