Channel noise in neurons.

By J. White, J. Rubinstein, A. Kay. Trends in Neurosciences, 2000

683 citations recorded by the source corpus.

The probabilistic gating of voltage-dependent ion channels is a source of electrical 'channel noise' in neurons. This noise has long been implicated in limiting the reliability (repeatability) of neuronal responses to repeated presentations of identical stimuli. More recently, it has been shown to increase the range of spiking behaviors exhibited in some neural populations. Channel numbers are tied to metabolic efficiency and the stability of resting potential, and channel noise might be exploited by future cochlear implants in order to improve the temporal representation of sound.

Subfields: Cellular and Molecular Neuroscience, Cognitive Neuroscience, Statistical and Nonlinear Physics

View Paper: https://www.semanticscholar.org/paper/0116aa110b839a566dbb305c5855bf43c4014ac4

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In Cellular and Molecular Neuroscience

In Cognitive Neuroscience

In Statistical and Nonlinear Physics

Citations in the corpus

Stochastic resonance and sensory information processing: a tutorial and review of application. (2004, background): “…from sources such as ﬂuctuations in the transmitter quanta released by nerve terminals, number of activated postsynaptic receptors, ion concentrations, membrane conductance, effects of previous action potentials, etc. (Traynelis and Jaramillo, 1998; White et al., 1998, 2000; Koch and Segev, 2000).”
Interacting Particle Solutions of Fokker–Planck Equations Through Gradient–Log–Density Estimation (2020, background): “arising either from random fluctuations of constituent subsystems [4,5], or from fluctuating interactions with the environment [6,7].”
Noise in the nervous system (2008, background): “The most dominant source of such electrical noise is channel nois”
Control, exploitation and tolerance of intracellular noise (2002, background): “Other cellular processes influenced by noise include ion-channel gatin”
Neurophysiological and Computational Principles of Cortical Rhythms in Cognition (2010, background): “Subthreshold oscillations could subserve a signal carrier for phase-locking and resonance, by virtue of the cell’s sensitivity to small but precisely timed inputs (13, 106, 177, 217, 1048).”
A review for dynamics in neuron and neuronal network (2017, methodology): “For biological neuron, described by Hodgkin–Huxley model [1], channel noise [35] and temperature are important factors, which can change the excitability and modes in electrical activities, it often reads as follows where the variable V describes the membrane potential of the neurons, m , n and h…”